Simvastatin
- TRADE NAME: Denan; Inegy (Merck/Schering-Plough); Lipex; Liponorm; Lodales; Simcor (Abbott); Simovil; Sivastin; Vytorin (Merck/Schering-Plough); Zocor (Merck); Zocord
- INDICATIONS: Hypercholesterolemia
- CLASS: HMG-CoA reductase inhibitor, Statin
- HALF-LIFE: 1.9 hours
Alitretinoin, Amiodarone, Amlodipine, Atazanavir, Azithromycin, Boceprevir, Bosentan, Carbamazepine, Ciprofibrate, Clarithromycin, Clopidogrel, Colchicine, Conivaptan, Coumarins, Cyclosporine, Danazol, Darunavir, Dasatinib, Delavirdine, Diltiazem, Dronedarone, Efavirenz, Erythromycin, Fosamprenavir, Fusidic Acid, Gemfibrozil, Grapefruit Juice, HIV protease inhibitors, Imatinib, Imidazoles, Indinavir, Itraconazole, Ketoconazole, Lopinavir, Miconazole, Nefazodone, Nelfinavir, Paclitaxel, Posaconazole, Rabeprazole, Ranolazine, Red Rice Yeast, Rifampin, Ritonavir, Roxithromycin, Saquinavir, Selenium, St John's Wort, Tacrolimus, Telaprevir, Telithromycin, Ticagrelor, Tipranavir, Triazoles, Verapamil, Warfarin
PREGNANCY CATEGORY: X
Simcor is simvastatin and niacin; Vytorin is simvastatin and ezetimibe.
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Click on the DRUG REVIEW ARTICLE tab (above) to see a review of simvastatin in the Informa Healthcare journal Expert Opinion on Drug Safety. (Note that non-subscribers to the journal will only be able to see an abstract of the article.)
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Incidence 
- <1%
- 1-5%
- 5-10%
- 10-15%
- 15-20%
- 20-30%
- >30%
Seriousness
- Hospitalization possible
- Life Threatening
- Fatal
Warnings in other populations
- Breast feeding
- Geriatric
- Pediatric