Lisinopril

Breastfeeding Pediatric
  • TRADE NAME: Acerbon; Alapril; Carace; Coric; Prinil; Prinivil (Merck); Prinzide (Merck); Tensopril; Vivatec; Zestoretic (AstraZeneca); Zestril (AstraZeneca)
  • INDICATIONS: Hypertension; as adjunctive therapy in the management of heart failure; short-term treatment following myocardial infarction in hemodynamically stable patients
  • CLASS: Angiotensin-converting enzyme (ACE) inhibitor
  • HALF-LIFE: 12 hours
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:

Alcohol, Aldesleukin, Allopurinol, Alpha blockers, Alprostadil, Amifostine, Amiloride, Angiotensin II receptor antagonists, Antacids, Antidiabetics, Antihypertensives, Antipsychotics, Anxiolytics and hypnotics, Aprotinin, Azathioprine, Baclofen, Beta blockers, Calcium channel blockers, Clonidine, Corticosteroids, Cyclosporine, Diazoxide, Diuretics, Eplerenone, Estrogens, Everolimus, Garlic, General anesthetics, Gold and Gold Compounds, Heparins, Herbals, Hydralazine, Hypotensives, Insulin, Levodopa, Liraglutide, Lithium, MAO inhibitors, Metformin, Methyldopa, Methylphenidate, Minoxidil, Moxisylyte, Moxonidine, Nitrates, Nitroprusside, NSAIDs, Pentoxifylline, Phosphodiesterase 5 inhibitors, Potassium salts, Prostacyclin analogues, Rituximab, Salicylates, Sirolimus, Spironolactone, Sulfonylureas, Temsirolimus, Tizanidine, Tolvaptan, Triamterene, Trimethoprim, Yohimbine

PREGNANCY CATEGORY: D

category C in first trimester; category D in second and third trimesters

Contraindicated in patients with a history of angioedema related to previous treatment with an ACE inhibitor and in patients with hereditary or idiopathic angioedema.

Safety and effectiveness in pediatric patients <6 years of age have not been established.

Prinzide and Zestoretic are lisinopril and hydrochlorothiazide.

Our database has 130 adverse reactions for this drug across the following areas

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SKIN
HAIR
MUCOSAL
CARDIOVASCULAR
CENTRAL NERVOUS SYSTEM
NEUROMUSCULAR/SKELETAL
GASTROINTESTINAL/HEPATIC
RESPIRATORY
ENDOCRINE/METABOLIC
GENITOURINARY
RENAL
HEMATOLOGIC
OTIC
OCULAR
OTHER
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Incidence info

  • <1%
  • 1-5%
  • 5-10%
  • 10-15%
  • 15-20%
  • 20-30%
  • >30%

Seriousness info

  • Hospitalization possible
  • Life Threatening
  • Fatal

Warnings in other populations info

  • Breast feeding
  • Geriatric
  • Pediatric